A man opened fire with a rifle at a drug-testing clinic near Portland, Ore., killing his estranged wife and apparently taking his own life, officials said.

Robert Beiser, 39, fired multiple shots just before noon Tuesday inside the Legacy MetroLab in Tualatin, Ore., police Chief Kent Barker said, The (Portland) Oregonian reported.

His estranged wife, Teresa Beiser, 36, of Gladstone, was working at the clinic when she was fatally shot, police said. Two of her co-workers were wounded -- a 63-year-old man who suffered multiple gunshot wounds and was flown to the Oregon Health & Science University Hospital in Portland, and a 20-year-old woman who was taken by ambulance to the Legacy Emanuel Hospital in Portland after fleeing to a restaurant near the clinic.

Robert Beiser was found dead at the scene, apparently of a self-inflicted gunshot wound, Barker said.

A week ago, Teresa Beiser filed for divorce from her husband of 15 years, who worked as a car appraiser and as an independent contractor for the Oregonian, the newspaper said.

They had two children, a 14-year-old daughter, Nicole, and her 11-year-old brother, Drew.

The shooting marked the first in the city of 26,000 since August 2001, the Oregonian said.