Controlling enzyme may slow cancer growth

NORMAN, Okla., Nov. 20 (UPI) --

Controlling a certain enzyme could inhibit growth of lung, breast, colon and pancreatic cancers, University of Oklahoma researchers said.

The researchers discovered that an enzyme called sFAP can act as a "scaffolding," helping cancer cells divide beyond their normal limits, intrude on and destroy adjacent tissues and spread to other locations in the body, Dr. Patrick McKee said in research published in the journal Blood and the Journal of Thrombosis and Haemostasis.

Enzymes are proteins that catalyze, or increase the rates of, chemical reactions in cells.

If this specific enzyme can be inhibited, then cancer might be slowed or halted, McKee said.

Combined with chemotherapy or radiation, a malignancy might actually be able to be cured, the researchers theorize.

"You'd be able to hold a cancer in check," McKee told The (Oklahoma City) Oklahoman.

Their work "has attracted the attention of a number of pharmaceutical companies," he added.

The researchers received a $365,000 grant from the U.S. Defense Department to work at the University of Arkansas Medical Center.


Copyright 2008 by United Press International
All Rights Reserved.

Times of the Internet, now in Spanish


Published: Thursday 20th of November 2008 04:45:28 PM
Print | Email Friend |
Receive updates via Twitter

Like this article? Then submit it to your favorite social network to share with others.
Bookmark and Share
Subscribe to Health RSS Feed: rss feed health
Read more news stories in health.

Read the last five articles in the HEALTH category